Gene Sequence Polymorphisms Mutations in PFMDR-1 and PFCRT-O Genes of Plasmodium falciparum
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چکیده
Malaria is a life-threatening disease caused by parasites that are transmitted to people through the bites of infected female mosquitoes. According to WHO about 3.2 billion people (almost half of the world’s population) are at risk of malaria, approximate 300-500 million malaria cases occurred every year, 90% of the total cases occurred in Africa and Asia. 700,000 to 2.7 million cases mortality occurred worldwide (Kumar et al., 2007). According to UNICEF a child dies at every minute from malaria in International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 5 Number 10 (2016) pp. 451-458 Journal homepage: http://www.ijcmas.com
منابع مشابه
Sequence analysis of coding DNA fragments of pfcrt and pfmdr-1 genes in Plasmodium falciparum isolates from Odisha, India.
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Drug resistance is probably the greatest challenge to most malaria-control programs. Given the limited resources for other malarial-control measures, rational drug used is crucial. Molecular markers for parasite resistance such as pfcrt, pfmdr-1, and dhfr have the potential to be used in an integrated fashion to provide timely information that is useful to policy makers. Therefore, we evaluated...
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تاریخ انتشار 2016